
| AURY
LOR HOLTZMAN, M.D. #1 RECOMMENDED So. Calif. MARIJUANA DOCTOR |
"Overdose
deaths involving opioid pain relievers now exceed deaths from heroin and
cocaine combined." |
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| 17822 Beach
Blvd, Suite 330 Huntington Beach, CA 92647 |
Phone:
(714)375-4745 Fax: (714)842-4946 E-Mail: AuryLorHoltzmanMD@hotmail.com |
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| HOME | DOCTOR'S BLOGS | FORMS | DISPENSARY VERIFICATION | LEGAL | LINKS |
| DIRECTIONS | ABOUT US | CONTACT US | REVIEWS | SUBOXONE | PHOTOS |
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Dr. Aury Holtzman was one of the first few local physicians DEA certified to prescribe Suboxone about ten years ago, when Suboxone became available. He has used Suboxone for his private patients, treated patients at several drug and alcohol rehab facilities, and has worked at a methadone clinic. It is very important to be treated by a physician, like Dr. Holtzman, who is experienced and knowledgeable helping patients to detoxify. In addition, Dr. Aury Holtzman has over 25 years of extremely varied medical experience. You will be seen by a caring knowledgeable physician for the safest and best possible results. We understand that you may have an urgent need for Suboxone. We will make every effort to see you as soon as possible
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SUBOXONE is used to treat opioid dependence in an office-based setting, and can also be prescribed for take-home use. SUBOXONE suppresses symptoms of opioid withdrawal and decreases the cravings for opioids. SUBOXONE mostly is buprenorphine, a partial opioid that stimulates the activity of opioid receptors without producing the same maximal effects as with oxycodone or heroin. SUBOXONE also can be used to treat addiction to Vicodin, Percocet, or methadone. SUBOXONE contains naloxone, which is meant to discourage people from dissolving the tablet and injecting it into their system. If a person injects the SUBOXONE, the naloxone can cause a person dependent on a full opioid to quickly go into withdrawal. Taking SUBOXONE will result in almost immediate relief from opioid withdrawal. Discontinuing SUBOXONE abruptly can cause withdrawal symptoms, so when you are ready, your doctor will gradually taper your SUBOXONE dose. Depending on the individual patient, it may be several weeks to several months before you can stop taking SUBOXONE. A physician experienced with SUBOXONE can guide you through this period. |
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Opioid
receptor unsatisfied -- Withdrawal.
As someone becomes “tolerant” to opioids their opioid receptors
become less sensitive. More opioids are then required to produce the
same effect. Once “physically dependent” the body can no longer
manufacture enough natural opioids to keep up with this increased
demand. Whenever there is an insufficient amount of opioid receptors
activated, the body feels pain. This is withdrawal. Courtesy of NAABT, Inc (Naabt.org) |
Opioid
receptor satisfied with a full-agonist opioid.
The strong opioid effect of heroin and painkillers stops the withdrawal
for a period of time (4-24 hours). Initially, euphoric effects can be
felt. However, after prolonged use, tolerance and physical dependence
can develop. Now, instead of producing a euphoric effect, the opioids
are primarily just preventing withdrawal symptoms. Courtesy of NAABT, Inc (Naabt.org) |
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Opioids
replaced and blocked by buprenorphine. Buprenorphine
competes with the full
agonist opioids for
the receptor. Since buprenorphine has a higher affinity (stronger binding ability) it expels
existing opioids and blocks others from attaching. As a partial agonist, the buprenorphine has a limited opioid
effect, enough to stop withdrawal but not enough to cause intense
euphoria. Courtesy of NAABT, Inc (Naabt.org) |
Over
time (24-72 hours) buprenorphine dissipates, but
still creates a limited opioid effect (enough to prevent withdrawal) and
continues to block other opioids from attaching to the opioid receptors. Courtesy of NAABT, Inc (Naabt.org) |