"Overdose deaths involving opioid pain relievers now exceed deaths from heroin and cocaine combined." 
Internal Medicine News, 11/15/11, p.51

17822 Beach Blvd, Suite 330
Huntington Beach, CA 92647
Phone: (714)375-4745   Fax: (714)842-4946
E-Mail: [email protected]


Dr. Aury Holtzman was one of the first few local physicians DEA certified to prescribe Suboxone about ten years ago, when Suboxone became available. He has used Suboxone for his private patients, treated patients at several drug and alcohol rehab facilities, and has worked at a methadone clinic. It is very important to be treated by a physician, like Dr. Holtzman, who is experienced and knowledgeable helping patients to detoxify.  In addition, Dr. Aury Holtzman has over 25 years of extremely varied medical experience. You will be seen by a caring knowledgeable physician for the safest and best possible results.

We understand that  you may have an urgent need for Suboxone. We will make every effort to see you as soon as possible



SUBOXONE is used to treat opioid dependence in an office-based setting,  and can also be prescribed for take-home use.  SUBOXONE suppresses symptoms of opioid withdrawal and  decreases the cravings for opioids. SUBOXONE mostly is buprenorphine, a partial opioid that stimulates the activity of opioid receptors without producing the same maximal effects as with oxycodone or heroin. SUBOXONE also can be used to treat addiction to Vicodin, Percocet, or methadone. 

SUBOXONE  contains naloxone, which is meant to discourage people from dissolving the tablet and injecting it into their system. If a person injects the SUBOXONE, the naloxone can cause a person dependent on a full opioid to quickly go into withdrawal.

Taking SUBOXONE will result in almost immediate relief from opioid withdrawal. Discontinuing SUBOXONE abruptly can cause withdrawal symptoms, so when you are ready, your doctor will gradually taper your SUBOXONE dose. Depending on the individual patient, it may be several weeks to several months before you can stop taking SUBOXONE. A physician experienced with SUBOXONE can guide you through this period

Opioid receptor unsatisfied -- Withdrawal. As someone becomes �tolerant� to opioids their opioid receptors become less sensitive. More opioids are then required to produce the same effect. Once �physically dependent� the body can no longer manufacture enough natural opioids to keep up with this increased demand. Whenever there is an insufficient amount of opioid receptors activated, the body feels pain. This is withdrawal.
Courtesy of NAABT, Inc (
Opioid receptor satisfied with a full-agonist opioid. The strong opioid effect of heroin and painkillers stops the withdrawal for a period of time (4-24 hours). Initially, euphoric effects can be felt. However, after prolonged use, tolerance and physical dependence can develop. Now, instead of producing a euphoric effect, the opioids are primarily just preventing withdrawal symptoms.

Courtesy of NAABT, Inc (
Opioids replaced and blocked by buprenorphine. Buprenorphine competes with the full agonist opioids for the receptor. Since buprenorphine has a higher affinity (stronger binding ability) it expels existing opioids and blocks others from attaching. As a partial agonist, the buprenorphine has a limited opioid effect, enough to stop withdrawal but not enough to cause intense euphoria.
Courtesy of NAABT, Inc (
Over time (24-72 hours) buprenorphine dissipates, but still creates a limited opioid effect (enough to prevent withdrawal) and continues to block other opioids from attaching to the opioid receptors.
Courtesy of NAABT, Inc (